Does Puzzle Agent work for anyone with a MBP Retina? On the second puzzle, no logs show up.
I don't have a MBP, but I have the same issue on a 27" LED Cinema Display. It appears to be an old bug that Telltale supposedly fixed late 2010. I've emailed both steam and telltale with no response as of yet.
Update: I have now received an update from Telltale apologizing for the error and asking me to delete the game and save files, exit steam, reboot computer, and re-download puzzle agent. It made no change, and I'm waiting for the next reply from Telltale.
Update #2: Telltale has informed me that this is, in fact, the scene render glitch that was patched for PC in late 2010. Unfortunately, Telltale has no plans to patch the Mac version.